As a comprehensive agenda for economic transition, the Research and Innovation Strategies for Smart Specialisation -RIS3 incorporates a dynamic monitoring mechanism with reliable indicators and statistics in order to keep it current, smart and sustainable over time.

The National Documentation Centre (EKT), producer of official national statistics on Research, Technology, Development and Innovation (RTDI), is the source of indicators on national and corresponding regional strategies RIS3,  the Operational Programme Competitiveness, Entrepreneurship and Innovation 2014-2020 (EPAnEK) and the Regional Operational Programs. EKT also collaborates with the EU's Joint Research Centre for specialized regional performance issues.
More specifically, EKT produces and publishes the following indicators for RIS3 results which are listed in Appendices I and II of the document  "Monitoring System & Evaluation of Strategic RIS3 2014-2020 '' of the Special Service for Strategy, Planning and Evaluation / NSRF National Coordination Authority, General Investment-ECAC Secretariat / Ministry of Economy and Development.  The names of the indicators are in correspondence with said document.